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Cellular and Organismal Biology

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Aging is an extremely complex process, affecting individual cells andrnorganisms as a whole. Here we discuss the impact of telomeres, the natural chromosome ends, on cellular and organismal aging, and how telomere maintenance influencesrngenome stability and tumorigenesis. Since telomeres represent only a fraction of therncomplexity of the aging process, we discuss how genome integrity and DNA damagernresponse pathways affect postmitotic aging, and which genetic pathways promote survival and elongated life, namely the IGF-1 signaling pathway, dietary restriction, andrnmitochondrial transport chain. At this point the researchers in the field are intenselyrnstudying individual aspects of aging, but it remains a unique challenge to integrate allrnaspects, with the goal of understanding longevity

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

570 Don c

Penerbit

San Francisco : W.H. Freeman and Company., 1974

Deskripsi Fisik

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Bahasa

English

ISBN/ISSN

0-7167-0894-9

Klasifikasi

570

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

Organismal

Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

Lampiran Berkas

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